Clinical characteristics and therapeutic procedure for four cases with 2019 novel coronavirus pneumonia receiving combined Chinese and Western medicine treatment.
Identifieur interne : 000A18 ( Main/Exploration ); précédent : 000A17; suivant : 000A19Clinical characteristics and therapeutic procedure for four cases with 2019 novel coronavirus pneumonia receiving combined Chinese and Western medicine treatment.
Auteurs : Zhenwei Wang [République populaire de Chine] ; Xiaorong Chen [République populaire de Chine] ; Yunfei Lu [République populaire de Chine] ; Feifei Chen [République populaire de Chine] ; Wei Zhang [République populaire de Chine]Source :
- Bioscience trends [ 1881-7823 ] ; 2020.
Descripteurs français
- KwdFr :
- Adulte, Adulte d'âge moyen, Antiviraux (usage thérapeutique), Association médicamenteuse, Chine, Femelle, Humains, Indoles (usage thérapeutique), Infections à coronavirus (traitement médicamenteux), Jeune adulte, Lopinavir (usage thérapeutique), Mâle, Médicaments issus de plantes chinoises (usage thérapeutique), Pneumopathie virale (traitement médicamenteux), Ritonavir (usage thérapeutique), Études rétrospectives.
- MESH :
- traitement médicamenteux : Infections à coronavirus, Pneumopathie virale.
- usage thérapeutique : Antiviraux, Indoles, Lopinavir, Médicaments issus de plantes chinoises, Ritonavir.
- Adulte, Adulte d'âge moyen, Association médicamenteuse, Chine, Femelle, Humains, Jeune adulte, Mâle, Études rétrospectives.
- Wicri :
- geographic : République populaire de Chine.
English descriptors
- KwdEn :
- Adult, Antiviral Agents (therapeutic use), Betacoronavirus, China, Coronavirus Infections (drug therapy), Drug Combinations, Drugs, Chinese Herbal (therapeutic use), Female, Humans, Indoles (therapeutic use), Lopinavir (therapeutic use), Male, Middle Aged, Pneumonia, Viral (drug therapy), Retrospective Studies, Ritonavir (therapeutic use), Young Adult.
- MESH :
- chemical , therapeutic use : Antiviral Agents, Drugs, Chinese Herbal, Indoles, Lopinavir, Ritonavir.
- geographic : China, Drug Combinations.
- drug therapy : Coronavirus Infections, Pneumonia, Viral.
- Adult, Betacoronavirus, Female, Humans, Male, Middle Aged, Retrospective Studies, Young Adult.
Abstract
Pneumonia associated with the 2019 novel coronavirus (2019-nCoV) is continuously and rapidly circulating at present. No effective antiviral treatment has been verified thus far. We report here the clinical characteristics and therapeutic procedure for four patients with mild or severe 2019-nCoV pneumonia admitted to Shanghai Public Health Clinical Center. All the patients were given antiviral treatment including lopinavir/ritonavir (Kaletra®), arbidol, and Shufeng Jiedu Capsule (SFJDC, a traditional Chinese medicine) and other necessary support care. After treatment, three patients gained significant improvement in pneumonia associated symptoms, two of whom were confirmed 2019-nCoV negative and discharged, and one of whom was virus negative at the first test. The remaining patient with severe pneumonia had shown signs of improvement by the cutoff date for data collection. Results obtained in the current study may provide clues for treatment of 2019-nCoV pneumonia. The efficacy of antiviral treatment including lopinavir/ritonavir, arbidol, and SFJDC warrants further verification in future study.
DOI: 10.5582/bst.2020.01030
PubMed: 32037389
Affiliations:
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Le document en format XML
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Health Clinical Center, Shanghai, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Traditional Chinese Medicine, Shanghai Public Health Clinical Center, Shanghai</wicri:regionArea><wicri:noRegion>Shanghai</wicri:noRegion></affiliation></author><author><name sortKey="Chen, Feifei" sort="Chen, Feifei" uniqKey="Chen F" first="Feifei" last="Chen">Feifei Chen</name><affiliation wicri:level="1"><nlm:affiliation>Department of Respiratory Disease, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Respiratory Disease, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai</wicri:regionArea><wicri:noRegion>Shanghai</wicri:noRegion></affiliation></author><author><name sortKey="Zhang, Wei" sort="Zhang, Wei" uniqKey="Zhang W" first="Wei" last="Zhang">Wei Zhang</name><affiliation wicri:level="1"><nlm:affiliation>Department of Respiratory Disease, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, China.</nlm:affiliation><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Respiratory Disease, Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai</wicri:regionArea><wicri:noRegion>Shanghai</wicri:noRegion></affiliation></author></analytic><series><title level="j">Bioscience trends</title><idno type="eISSN">1881-7823</idno><imprint><date when="2020" type="published">2020</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Antiviral Agents (therapeutic use)</term><term>Betacoronavirus</term><term>China</term><term>Coronavirus Infections (drug therapy)</term><term>Drug Combinations</term><term>Drugs, Chinese Herbal (therapeutic use)</term><term>Female</term><term>Humans</term><term>Indoles (therapeutic use)</term><term>Lopinavir (therapeutic use)</term><term>Male</term><term>Middle Aged</term><term>Pneumonia, Viral (drug therapy)</term><term>Retrospective Studies</term><term>Ritonavir (therapeutic use)</term><term>Young Adult</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Antiviraux (usage thérapeutique)</term><term>Association médicamenteuse</term><term>Chine</term><term>Femelle</term><term>Humains</term><term>Indoles (usage thérapeutique)</term><term>Infections à coronavirus (traitement médicamenteux)</term><term>Jeune adulte</term><term>Lopinavir (usage thérapeutique)</term><term>Mâle</term><term>Médicaments issus de plantes chinoises (usage thérapeutique)</term><term>Pneumopathie virale (traitement médicamenteux)</term><term>Ritonavir (usage thérapeutique)</term><term>Études rétrospectives</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Antiviral Agents</term><term>Drugs, Chinese Herbal</term><term>Indoles</term><term>Lopinavir</term><term>Ritonavir</term></keywords><keywords scheme="MESH" type="geographic" xml:lang="en"><term>China</term><term>Drug Combinations</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Coronavirus Infections</term><term>Pneumonia, Viral</term></keywords><keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Infections à coronavirus</term><term>Pneumopathie virale</term></keywords><keywords scheme="MESH" qualifier="usage thérapeutique" xml:lang="fr"><term>Antiviraux</term><term>Indoles</term><term>Lopinavir</term><term>Médicaments issus de plantes chinoises</term><term>Ritonavir</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Betacoronavirus</term><term>Female</term><term>Humans</term><term>Male</term><term>Middle Aged</term><term>Retrospective Studies</term><term>Young Adult</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Association médicamenteuse</term><term>Chine</term><term>Femelle</term><term>Humains</term><term>Jeune adulte</term><term>Mâle</term><term>Études rétrospectives</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>République populaire de Chine</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Pneumonia associated with the 2019 novel coronavirus (2019-nCoV) is continuously and rapidly circulating at present. No effective antiviral treatment has been verified thus far. We report here the clinical characteristics and therapeutic procedure for four patients with mild or severe 2019-nCoV pneumonia admitted to Shanghai Public Health Clinical Center. All the patients were given antiviral treatment including lopinavir/ritonavir (Kaletra<sup>®</sup>), arbidol, and Shufeng Jiedu Capsule (SFJDC, a traditional Chinese medicine) and other necessary support care. After treatment, three patients gained significant improvement in pneumonia associated symptoms, two of whom were confirmed 2019-nCoV negative and discharged, and one of whom was virus negative at the first test. The remaining patient with severe pneumonia had shown signs of improvement by the cutoff date for data collection. Results obtained in the current study may provide clues for treatment of 2019-nCoV pneumonia. The efficacy of antiviral treatment including lopinavir/ritonavir, arbidol, and SFJDC warrants further verification in future study.</div></front></TEI><affiliations><list><country><li>République populaire de Chine</li></country></list><tree><country name="République populaire de Chine"><noRegion><name sortKey="Wang, Zhenwei" sort="Wang, Zhenwei" uniqKey="Wang Z" first="Zhenwei" last="Wang">Zhenwei Wang</name></noRegion><name sortKey="Chen, Feifei" sort="Chen, Feifei" uniqKey="Chen F" first="Feifei" last="Chen">Feifei Chen</name><name sortKey="Chen, Xiaorong" sort="Chen, Xiaorong" uniqKey="Chen X" first="Xiaorong" last="Chen">Xiaorong Chen</name><name sortKey="Lu, Yunfei" sort="Lu, Yunfei" uniqKey="Lu Y" first="Yunfei" last="Lu">Yunfei Lu</name><name sortKey="Zhang, Wei" sort="Zhang, Wei" uniqKey="Zhang W" first="Wei" last="Zhang">Wei Zhang</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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